Paraphyletic

Medicine and human biology
Male contraception tends to take one of two forms: condoms or pulling out.
Neither is popular with guys, but it beats having to buy and remember to take pills, amirite, guys?
I know, ladies. It’s not fair. You feel shafted. But take heart. A number of labs have been hard at work developing contraceptive drugs for dudes. On Monday, at The Endocrine Society’s annual meeting in Houston, Christine Wang of Harbor-UCLA Medical Center reported preliminary data from a new study of a contraceptive gel containing two sex hormones, testosterone and nestorone. The gel is “applied to the skin.” What skin, I’m not sure. I guess we should assume… the scrotal area. Anyway, the Endocrine Society posted a press release here. 
Here’s the thrust: of the 50-or-so guys who, for 20 weeks, applied a gel containing testosterone and 12 mg of nestorone, nearly 90 percent saw their sperm counts go below 1 million sperm per 1 mL of ejaculate. That may sound like a lot of sperm, but the average ejaculate is about 3.5 mL semen containing 250 million sperm. So 1 million sperm/1 mL ejaculate is a 98.6 percent reduction. That’s beyond the danger zone for the sad sacks who are actually trying to make a baby.
Nestorone is a synthetic sex hormone that has been approved by the FDA for research, but has not yet approved it for products you can actually buy. Crazily, nestorone was developed by a nonprofit in New York, the Population Council.

Male contraception tends to take one of two forms: condoms or pulling out.

Neither is popular with guys, but it beats having to buy and remember to take pills, amirite, guys?

I know, ladies. It’s not fair. You feel shafted. But take heart. A number of labs have been hard at work developing contraceptive drugs for dudes. On Monday, at The Endocrine Society’s annual meeting in Houston, Christine Wang of Harbor-UCLA Medical Center reported preliminary data from a new study of a contraceptive gel containing two sex hormones, testosterone and nestorone. The gel is “applied to the skin.” What skin, I’m not sure. I guess we should assume… the scrotal area. Anyway, the Endocrine Society posted a press release here

Here’s the thrust: of the 50-or-so guys who, for 20 weeks, applied a gel containing testosterone and 12 mg of nestorone, nearly 90 percent saw their sperm counts go below 1 million sperm per 1 mL of ejaculate. That may sound like a lot of sperm, but the average ejaculate is about 3.5 mL semen containing 250 million sperm. So 1 million sperm/1 mL ejaculate is a 98.6 percent reduction. That’s beyond the danger zone for the sad sacks who are actually trying to make a baby.

Nestorone is a synthetic sex hormone that has been approved by the FDA for research, but has not yet approved it for products you can actually buy. Crazily, nestorone was developed by a nonprofit in New York, the Population Council.

  1. corgiaddict said: long term effects are going to be hard to prove.
  2. bornforhardluck said: There is another male cotraceptive that is injected. It is still in clinical trials at this time. I forget the details but, it lines the vas defrons and obliterates sperm. The injection is reversible as well. Pretty sweet shit if you ask me.
  3. paraphyletic posted this